Hyperpolarized carbon-13 MRI for very early response assessment of neoadjuvant chemotherapy in breast cancer patients

Hyperpolarized ¹³C-MRI is an emerging tool for probing tissue metabolism by measuring ¹³C-label exchange between intravenously injected hyperpolarized [1–¹³C]pyruvate and endogenous tissue lactate. Here, we demonstrate that hyperpolarized ¹³C-MRI can be used to detect early response to neoadjuvant therapy in breast cancer.

Media coverage for this publication in the Sunday Times.