Integrating radiomics and ctDNA data in Ovarian cancer

Patients with findings suspicious for ovarian cancer or with a definite diagnosis of the disease usually undergo computed tomography (CT) scans as their standard-of-care imaging to assess the extent of the disease. We are collaborating with molecular oncology and computational groups to extract quantitative data from these images (radiomics) and combine them with ctDNA isolated from blood samples of these patients to develop tools that predict response to chemotherapy as well as survival in these patients. These studies also help us understand which features of ovarian cancer affect the extent of ctDNA shedding into circulation and how molecular features of ovarian cancer affect tumour appearance on imaging.

Further information on the Integration of Radiomics and Circulating Tumour DNA (ctDNA) project.